The name of this William Jones’ first wife is not known.

Morgan Co. death records list William Jones, age 66, died 14 May 1852 in Carter Co., residence Morgan Co., born Virginia, cause of death consumption, parents Ambroce & Martha Jones.

1830 census of Morgan Co., lists on p. 66, line 10:
William Jones, 2 m 5-9, 1 m 10-15, 1 m 40-49, 1 f 5-9, 1 f 15-19, 1 f 40-49.
This is likely to be Ambrose Jones' son William b. 1785 (who would be 45 in 1830, and whose known sons Isaac and William would be respectively about 9 and 5 in 1830.) The two daughters and the son age 10-15 have not been identified. There may also be older children who had left home by 1830.

There was another William Jones living very nearby who was about 20 years older. See census notes for William Jones b. ca 1764 for comparison.

1840 census of Morgan Co., p. 323, line 7, lists family:
Wm Jones, 1 m 10-14, 1 m 15-19, 1 m 50-59, 1 f 10-14, 1 f 20-29, 1 f 50-59. This appears to be the same as the younger William Jones family from the 1830 census.

This William Jones was living with his son Isaac in the 1850 census of Morgan Co.