Be careful not to confuse her with Nancy Ellen Ferguson who married John E. Ison.

Her death certificate records Nancy E. Isom, age 42 years 6 months 1 day, born 23 Sep 1886 in Morgan Co., Ky, died 24 Mar 1929 in Rowan Co., Ky, married, wife of John Isom, father Isaac Conley, mother’s maiden name Emily Fyffe, both born in Morgan Co., Ky, cause of death Pul. T.B., informant John Isom, Clearfield, Ky, burial in Bradley Cemetery.

The year of birth is probably off by one or even two; she was recorded in the 1900 census, taken in June, as age 14 born Sep 1885, and on her marriage license in November 1900 as age 16.

Morgan Co., Ky marriage records list the marriage on 13 Nov 1900 of John Isom, age 21, and Nancy E. Conley, age 16, both residents of Morgan Co.

I mainly have this family in my database because my first cousin three times removed, Lou Ginter, married a John Ison as her second husband, but I don’t know which one. So I’m entering all the John Isons in the Morgan/Rowan/Elliott county area of that generation.

Also, their granddaughter Geneva Buckner, daughter of Lola Ison, married my 4C1R Glenvill Wallace.

In 1910 John and Nancy are living with his parents:

1910 census of Elliott Co., Ky, precinct 3, enumerated 21 April, lists on p. 2B as family #33:
Ison, Argalus, 52, farmer; Melissa, wife, 52, first marriage for both, married 32 years, mother of 8 children, 4 living; Anna, dau, 16; John, son, 29; Nancy E, dau-in-law, 34, first marriage for both, married 9 years, mother of 4 children, 4 living; Melissa E., granddau, 8; George W., grandson, 5; Lola, granddau, 3; Argalus, grandson, 6/12. All born Ky Ky Ky.

1920 census of Elliott Co., Ky, Sandy Hook precinct, enumerated 21 Jan, lists on p. 5B as family #93:
Ison, John, 35, laborer farm work; Nancy E., wife, 32; George, son, 14; Lola, dau, 13; Gale, son, 11; Delpha, dau, 8; Gussie, son, 6; Levadie, dau, 3 4/12. All born Ky Ky Ky.

(The ages are high for the children. Delpha was only 7, Guss a month short of 5, and Levada a month short of 2.)

I cannot find John or the younger children (Guss, Levada, Annie and Mary) in the 1930 census. (Gale and Delpha are both married and sharing a household.)